THERAPEUTIC POTENTIAL OF AYURVEDIC TREATMENT REGIME IN A PATIENT WITH AKI ON CKD STAGE V

Abstract

Aim: To evaluate the therapeutic potential of an integrative Ayurvedic treatment regimen in a patient with AKI on chronic kidney disease CKD stage V undergoing maintenance hemodialysis. Background: CKD is a progressive condition characterized by irreversible decline in renal function, often requiring renal replacement therapy in advanced stages. Acute kidney injury (AKI) superimposed on CKD further worsens clinical outcomes and is associated with high morbidity, poor symptom control, and increased dependence on dialysis. Evidence for complementary interventions that improve both clinical symptoms and biochemical parameters in this setting remains limited. This case highlights the potential role of individualized Ayurvedic therapy as a supportive modality. Case Description: A 63-year-old male, previously employed as a private bus driver, with diabetes, hypertension, and obstructive uropathy developed AKI on CKD stage V and was initiated on thrice-weekly hemodialysis. He presented with severe pruritus, dysuria, lower limb pain, fatigue, vertigo, and poor appetite. An integrative Ayurvedic regimen including Siddha kṣhīr-pāka formulations and herbomineral preparations was administered orally. Over two months, the patient showed marked symptomatic improvement. Serum creatinine reduced from 8.4 mg/dl during hospitalization to 2.02 mg/dl, with improvement in estimated GFR to 41 mL/min/1.73 m². Hemodialysis was discontinued, and no adverse events were reported. Conclusion: This case demonstrates significant symptomatic relief and notable biochemical improvement following integrative Ayurvedic intervention in a patient with AKI on CKD stage V. Clinical Significance: Ayurvedic therapy may serve as a safe, supportive adjunct for symptom control and possible renal function stabilization in advanced CKD with AKI, warranting further controlled clinical studies.