A CLINICAL STUDY TO EVALUATE THE EFFECT OF NAVAKA GUGGUL ON HYPERCHOLESTEROLEMIA- A SINGLE BLINDED PLACEBO CONTROLLED RANDOMIZED STUDY

Abstract

The plasma level of lipids is indicative of not only the severity of various co-morbid condi-tions such as Diabetes mellitus but also reflects the inherent genetic characteristic, lifestyle and food habits of an individual. A high level of Cholesterol is of prime concern as it is the solo risk factor for atherogenic diseases. The present study has been planned and carried out to evaluate the efficacy of Navaka guggul in the management of high cholesterol. After thorough review of both ancient and modern literatures, hypercholesterolemia can well be correlated with Poshaka (asthayi) meda vriddhi which is related to Kaphaj vikar in Ayurvedic system.Finally it can be concluded that the drug under study has shown enthusias-tic results in reducing the overall value of serum Cholesterol. 40% patients showed good ef-fect, 50% showed moderate effect and approximately 3% showed mild effect. Key words: Cholesterol, Kaphaj Vikar, Navaka Guggul, Meda vriddhi What's already known about this topic?: Various data from clinical and experimental studies have shown the relation between hyperlipidaemia and atherosclerotic diseases. Till date very little data is available on the effect of Navak Guggul on cholesterol levels. What does this study add?: The drug under trial has shown highly promising results in treating hypercholesterolemia, which should be further be evaluated on larger subjects. It has also opened the way for treatment of other kaphaj diseases which are result of deleterious food & lifestyle habits of modern society.