ANTIBACTERIAL ACTIVITY DECOCTION OF COSCINIUM FENESTRATUM ON STAPHYLOCOCCUS AUREUS:AN EXPERIMENTAL STUDY

Abstract

Coscinium fenestratum is one of the most important plants used in traditional systems of medicine. Pharmacological properties of the plant have been mentioned as Vranajit and Vrananut in Ayurveda classics especially including wound cleansing property. Unawareness of this, the plant has escaped utilization of C.fenestratum as anti bacterium. The current study focused on the bacterial wounds, by Staphylococcus aureus and the efficacy was evaluated using decoction of C.fenestratum as a washing agent. For antibacterial susceptibility test, testing drug was prepared in six different concentrations homogenously. Prepared decoctions of stem were tested for its potent antibacterial activity against proto type of S.aureus from laboratory specimens. Followed the Antibacterial Sensitivity Test, in duplicate discs of modified Agar well diffusion method on bacterial strains and assessed the efficacy comparing with positive control as Amoxicillin. The mean inhibitory zones in samples were measured as 15.5mm, 14.75mm, 20.25mm, 16.5mm, 12.5mm & 18.75mm respectively. All of the testing samples indicated significant antibacterial potential on laboratory specimens of S.aureus. The current experimental study has revealed that the stems of C. fenestratum have remarkable antibacterial effective on the S. aureus.