NIDANA KARATWA OF GRAHANI, ARSHAS AND ARBUDA W.S.R TO COLON CANCER

Abstract

In the pathogenesis of every disease Agni plays a vital role. Understanding of Agni in a subject must be the prime aim of a physician before planning the treatment. In case of Guda Pradeshagata Arbuda, Dhatwagnimandya which occurs as a sequel of Jataragnimandya can be considered. On a retrospective analysis it is evident that Grahani and Abhyantara Arshas have an inevitable role in the causation of Guda Pradeshagata Arbuda. Pathogenesis of all the above diseases initiates due to Agni Dusti. Metabolic derangement and adenomatous polyp along with altered gut micro biota contribute to the pathogenesis of colon cancer. Many studies have proved the involvement of gut brain axis in the causation of colon cancer.