PHARMACEUTICAL STANDARDIZATION OF SNUHI (EUPHORBIA NERIIFOLIA LINN.) KSHARA

Abstract

Snuhi Kshara is derivative of ash of Euphorbia neriifolia Linn. obtained in form of alkaline crystals. Standardization of Ayurvedic formulations is essential for establishing the quality, safety and efficacy of finished product which can be achieved by adopting Standard Manufacturing Process (SMP). Standardization of Snuhi Kshara is not attempted till date. The present research has been carried out to establish the Standard Manufacturing Process and preliminary analytical profile for Snuhi Kshara. Shuhi Panchanga was procured from Sundar Ayurved Pharmacy, J. S. Ayurved Mahavidyalaya, Nadiad. Kshara was prepared by method mentioned in the text Ayurved sara Samgraha with modification in soaking duration and preliminary analytical profile was developed. In this study, we attempted repeatedly (three times) washes of obtained ash to extract the maximum yield. It is found that maximum Kshara can be extracted by three consecutive washes. The final yield of Kshara was 18.47% w/w, 9.0% w/w and 2.18% w/w in three subsequent washes of obtained Ash. The preliminary analytical profile does not show any significant remarks in Kshara which obtained through three subsequent washes. Hence, multiple washes should be done to extract maximum amount of Kshara.