A PHARMACOGNOSTICAL AND PHYSICO-CHEMICAL ANALYSIS OF GUDUCHI MODAKA (VATI)

Abstract

Background: Guduchi Modaka is a Modaka Kalpana but it is formulated as Vati preparation due to its easy palatability of patients and its long term storage. Guduchi having Balya, Deepan-Pachana, Tridosha Shamaka and Rasayana property and its preparation i.e. Guduchi Modaka having Tridosha Shamaka and Rasayana property. Till date no published data is available on pharmacognostical and analytical profile of Guduchi Modaka, So present study is planned. Aims: To evaluate pharmacognostical and physico-chemical characters of Guduchi Modaka (Vati). Materials & Methods: Prepared drug was collected from pharmacy I.P.G.T. & R.A. and authenticated in respective Laboratory of I.P.G.T. & R.A., G.A.U., Jamnagar. Standard procedures were followed to undertake the pharmacognostical and physico-chemical analysis. Results: The phrmacognostical results of Guduchi Modaka showed Fibers of Guduchi, border-pitted vessels, simple starch grain etc. without staining and Lignified collenchyma cells, brown content of Guduchi after staining with (Phloroglucinol & Con. HCL). Physicochemical analysis of Guduchi Modaka revealed weight variation 28.45%, Hardness 1.95 kg/cm2, Disintrigation time ˃ 1 hr. etc., In HPTLC, Guduchi Modaka revealed 8 spots at 254 nm and 4 spots at 366 nm. Discussion: Pharmacognostical study helps in exact authentication of ingredients present in formulation through its organoleptic characters like taste, odor, color and touch along with microscopical characters and physico-chemical parameters. The presence of all contents of raw drugs in the final product shows the genuinity of the final product. All the pharmaceutical parameters analyzed showed values permissible for the Vati. Conclusion: As there are no reported study on the Guduchi Modaka, The findings of the study will be useful in the standardization of the drug and study might help as reference guidance for future scientific evaluations of the drug.