A COMPARATIVE PHARMACO-CLINICAL STUDY OF KASISA BHASMA PREPARED BY TWO METHODS W.S.R. TO PANDU ROGA [IRON DEFFICIENCY ANAEMIA]

Abstract

Iron deficiency anaemia is common throughout the world. Pandu Roga can be effectively compared with iron deficiency Anaemia on the grounds of its similar signs, and symptoms in the modern medicine. Iron compounds are widely prescribed in modern medicine for the treatment of Iron Deficiency Anaemia. Similarly, in Ayurveda we find many iron containing compound indicated for the treatment of Pandu Roga i.e. Lauha Bhasma, Mandura bhasma, Kasisa bhasma etc Kasisa Bhasma (Ferrous Sulphate), was selected for present study. Two different samples of Kasisa Bhasma was prepared by two different methods in which different Marana Dravyas were used, The study was planned to compare the therapeutic results of the two pharmaceutically different samples of Kasisa Bhasma with special reference to Marana Dravya i.e. Snuhipatra Swarasa and Nimbu Swarasa as referred in Rasa Tarangini (R.T. 21/255-258) and AFI (Rasamritam3/160) respectively, on sign and symptoms of Pandu Roga as mentioned in our classics and on Hb%. The study was conducted in two groups. In each group 15 patients were taken. Total 30 patients were selected for this study. Single blind study was designed. Hb% of patients calculated at 15th and 30th days. The results were analysed based on improvement in clinical features and increase in Hb% (Haemoglobin level) after treatment, and statistically analysed. Kasisa Bhasma referred by AFI was found more effective in subsidence of clinical sign and symptoms of Pandu Roga and in increasing Haemoglobin level and hence management of IDA.