ROLE OF AJAMOOTRA BHAVANA ON PHYSICO-CHEMICAL ASPECTS OF BILWADI AGADA WITH SPECIAL REFERENCE TO KALA (DURATION) – AN ANALYTICAL STUDY

Abstract

Background: Bilwadi Agada is indicated for the management of sarpa visha, lootavisha, Garavisha etc. It needs to be potentiated in order to increase its veerya. Bhavana samskara, is a wet trituration process and also considered as a size reduction technology, is an essential processing practice in preparation of Bilwadi Agada. Ambiguity in Protocol of bhavana samskara still prevails among Ayurveda fraternity as no specific time duration is indicated and hence need to be standardized with respect to safety and efficacy. Hence preclinical evaluation of Bilwadi agada is undertaken to standardize time duration of bhavana samskara by keeping particle size as analytical parameter. Aims and Objective: To evaluate the impact of Ajamootra bhavana on Physico-chemical and Phyto-chemical parameters of Bilwadi Agada and To evaluate variation in particle size of Bilwadi Agada depending upon different time interval of Bhavana samskara Methodology: Bilwadi Agada was prepared using Ajamootra bhavana in different time intervals. Three samples were analysed for physico and phytochemical parameters by keeping particle size as one of the investigating tool. Observation and Results: Qualitative analysis revealed presence of Carbohydrates, reducing sugar, alkaloids, proteins, amino acids, fats and oils, steroids, flavonoids, saponins, Carbonate, Iron, Chloride and Nitrate in all samples. Increase in particle size observed on time dependent manner with reference to bhavana samskara. Conclusion: particle size varies in relation with time duration, demands further studies.