International Journal of Applied Ayurved Research

COMPARATIVE CHROMATOGRAPHIC PROFILING OF DIFFERENT PHARMACEUTICAL PREPARATIONS MADE FROM ROOTS OF DESMODIUM GANGETICUM (L) DC(PRISNIPARNI) USING HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY

Mridula M K; P Y Ansary, Sara Monsy Oommen, Anuroopa G Nadh — Thu, 15 Jan 2026 00:00:00 +0530

Introduction: Ayurvedic literature emphasizes diverse pharmaceutical processes, including variations in solvents, heating techniques, and preparation media to optimize therapeutic benefits. Interestingly, the same plant part is often used in different dosage forms based on the disease context, indicating a strategic approach to enhance efficacy. Prisniparni is documented in classical Ayurvedic literature as a versatile drug, administered as formulations such as kwatha, ksheerapaka, and churna. The physicochemical properties of plant secondary metabolites influence disease modulation, and different preparation methods may cause structural modifications in these metabolites. However, such transformations remain underexplored. Aim: This study aimed to evaluate the phytochemical variation in Prisniparni rootwhen subjected to four preparation methods: methanolic extract, decoction (kwatha), traditional ksheerapaka, and a modified ksheerapaka made by mixing dried decoction powder with skimmed milk powder. Desmodium gangeticum (L.) DC. (Leguminosae), the accepted source of Prisniparni in Kerala, was used as the source drug in this study.

Materials and Methods: High-Performance Thin Layer Chromatography was employed to generate fingerprint profiles. Chromatographic separation was analyzed by comparing Rf values and visualizing bands under UV 254 nm and UV 366 nm. Results: Each formulation exhibited a unique set of bands, indicating substantial variation in phytochemical content. While some bands were common across preparations, others were formulation-specific, suggesting chemical transformation during the preparation process. Conclusions: The study demonstrates that pharmaceutical processing significantly alters the composition of chemical constituents in Prisniparni root. These findings support the Ayurvedic principle that preparation methods influence therapeutic potential. Further pharmacological investigations are essential to correlate these chemical differences with bioactivity and therapeutic relevance.

NUTRITIONAL ANALYSIS AND STABILITY TEST OF MASHADI MODAKA- AYURVEDIC FORMULATION AS NUTRITION SUPPLEMENT

Shalinee Mishra, Nikita Baghel, Anusree C — Thu, 15 Jan 2026 00:00:00 +0530

Background of the Study: Mashadi Modaka is indicated as one of the drugs for management of Karshya (underweight) and aphrodisiac wellbeing. Standardization and assurance of quality of herbal compounds Evaluation and Stability Assessment is needed. Aim and Objectives: To evaluate the Nutritional value and Stability of Mashadi Modaka. Material and methods: Test drug sample was prepared with Godhuma, Shali Tandula, Nistusha Masha (Urada), Yava etc. in the institutional pharmacy after that sample was analysed by using techniques like Spectrophotometry, Chromatography, and Titration methods. Result: Nutritional Analysis study showed that all the essential macronutrient and micronutrient available in Mashadi Modaka. Discussion and Conclusion: Mashadi Modaka provides 526.15 Kcal of energy per 100 grams, with 60.96 grams of carbohydrates, 10.39 grams of protein, and 26.75 grams of fat with appropriate shelf- life (Stability).

ANTI-MICROBIAL AND WOUND HEALING EFFICACY OF STHANIKA DHOOPANA IN WISTAR RATS USING EXCISION WOUND MODEL- AN IN VIVO STUDY

Geetanjali Sahu, Krishna Patel, Reetu Sharma, Gaurav Sharma — Thu, 15 Jan 2026 00:00:00 +0530

Background: Wound healing is a critical consideration in the field of surgery, and the primary goals are to prevent infection and expedite the healing process. Ancient Ayurvedic texts, such as those written by Acharya Sushruta, place significant emphasis on Vraṇa (wound) and its treatment. While many antiseptic agents are used to prevent infections, they often lack the ability to enhance the healing process and can even be harmful as they may have cytotoxic effects. In response to this, an innovative polyherbal formulation known as " Ġaṇa dhūpa "(Ayurvedic formulation fumigation) was developed for the practice of "Sthanika Dhūpana karma "(localized fumigation). The objective of this study aims to investigate the antimicrobial and wound healing effectiveness of Dhūpana karma using an excision wound model in Wistar rats.

Materials and method: Eighteen male Wistar rats were acquired for the study and divided into three groups, each containing six rats, all of which were infected with pre-sub cultured S. aureus bacteria. The test group received Sthānika Dhūpana, the control group was treated with Povidone iodine ointment, and the standard group received normal saline. Various parameters were assessed over a ten-day period and statistical analysis was performed to evaluate differences between the three groups at each time point.

Results: Significant results were observed in various parameters related to wound healing. The percentage of wound contraction rate was notably higher in the test group when compared to the other groups.

Conclusion: Dhūpana karma using Ġaṇa dhūpa is safe as well as effective in anti-microbial and wound healing activity.

MORPHOMETRIC ANALYSIS OF HUMERAL SHAFT DIMENSIONS AND TORSIONAL ANATOMY

Thu, 15 Jan 2026 00:00:00 +0530

The humerus, the longest bone of the upper limb, demonstrates significant anatomical variation, particularly in its length and rotational features. While maximum humeral length (MHL) and humeral biomechanical length (HBL) are commonly used in anthropometry and orthopedics, the humeral torsion angle (HTA) plays a vital role in shoulder mechanics and joint orientation. However, the interrelationship between these parameters remains underexplored. This study aims to assess the morphometric relationship between MHL, HBL, and HTA in adult human humeri and to determine whether humeral length influences torsional alignment. A total of 36 dry adult humeri (16 right-sided and 20 left-sided) were selected from the osteological collection of the National Institute of Ayurveda (NIA), Rajasthan. MHL, HBL, and HTA had been measured using standard osteometric procedures and digital imaging. Descriptive statistics and Pearson’s correlation coefficient were used to evaluate relationships among the parameters. The mean MHL was 30.99 ± 1.56 cm, HBL was 30.57 ± 1.51 cm, and HTA was 64.08° ± 9.23°. A very strong positive correlation was found between MHL and HBL (r = 0.99, p < 0.001), whereas weak, non-significant correlations were found between MHL and HTA (r = 0.10, p = 0.565) and between

HBL and HTA (r = 0.12, p = 0.479). Side-wise analysis revealed significantly greater MHL and HBL values in right-sided humeri compared to the left (p < 0.01), while HTA did not significantly differ between sides (p = 0.991). Side-related correlations between length parameters and HTA remained weak and statistically not significant. While MHL and HBL are closely related morphometric indicators, neither shows a significant influence on the humeral torsion angle. These findings suggest that torsion is anatomically and functionally independent from shaft length, emphasizing the need for individual assessment in clinical and surgical planning. Additionally, the detected side related asymmetry in humeral length parameters highpoints possible influences of limb dominance or usual use, while the consistent torsional values across sides emphasize the age-related stability of HTA as an independent anatomical trait.

INTEGRATING PREVENTIVE PRINCIPLES OF AYURVEDA INTO MODERN PUBLIC HEALTH DOMAINS: A NARRATIVE REVIEW AND PROPOSED CONCEPTUAL FRAMEWORK

Ravi Sharma, Samana Satyal, Kamakshi — Thu, 15 Jan 2026 00:00:00 +0530

Ayurveda, an ancient healthcare system extensively practiced in India and Nepal, has been increasingly explored for its potential role in addressing chronic lifestyle disorders. Public health, on the other hand, focuses on organized community efforts to prevent disease and promote well-being. This review article examines the connections between the health principles of Ayurveda and public health, illustrating how these two systems complement each other in promoting health and preventing disease. A thorough literature review of major Ayurvedic texts such as Charaka Samhita, Sushruta Samhita, Ashtanga Hridaya, Ashtanga Sangraha, and Bhavaprakasha Nighantu; a public health textbook and a few online databases such as PubMed, Cochrane Library, and Embase were conducted. This study identifies key areas where Ayurvedic principles align with public health practices, such as nutrition, physical activity, personal hygiene, environmental health, and reproductive health. The findings suggest that integrating Ayurvedic principles with modern public health strategies could enhance overall health outcomes. Therefore, based on this synthesis, a conceptual framework aligning Ayurvedic preventive principles with modern public health domains is proposed.

COMPARATIVE AND APPLIED STUDY BETWEEN CLASSICAL PHYSICS TO AYURVEDA W.S.R. TO LAWS OF MOTION IN RELATION WITH GURU, LAGHU, STHIRA, CHALA AND SAMSKARA GUNA

Darshini, Vasudev Chate, Shreevathsa — Thu, 15 Jan 2026 00:00:00 +0530

Introduction: “VEDA” derived from root ‘Vid’ meaning is ‘to Know’ or ‘Knowledge’. It can be considered as Ultimate science. The literatures derived after Veda are having impact of it. In the similar way the science and its branches are also having the impact of Veda. The ever-dynamic Science is originated from Latin verb ‘Scientia’ meaning is ‘to know’. For further in-depth study the science is subdivided into Physics, Chemistry and Biology. Physics is a branch of Science, it means Nature. In Physics all the concepts are in terms of theories or laws. Mechanic branch of Physics deals with the motion of an object with or without the reference of force, i.e. Newtons laws of motion and the Law of gravitation is concerned with motion(or equilibrium)of particles. These Law can be substantiated with Guna Siddhanta. Among Gunas Sthira(Stable), Chala(Moving), Guru(Heavy), Laghu(Light) and Samskara Gunas(Restoration-qualities) are having the similar properties and functions explained in the Newtons law of Motion. Aims & Objectives : To understand the application of Laws of motion with respect to Gurvadi Guna. Materials & Methods: Literary study has been done by Classical texts of Ayurveda, Tarka Sanghraha, Padartha Vijnana Books and 11^th NCERT text book of Physics. Discussion: The concepts of Sthira, Chala Guna compared with Sthira Dosha Chalana by Vata Dosha(1^st law of motion),Concept of Anupana(Adjuvant) & Akta Lavana Taila(Salt-mixed-oil) application compared to 2^nd law of motion and Guru-Laghu Guna(Nidana Sevena) respective changes in the body compared with 3^rd law of motion. Results: A brief review of literature was done and found that Newtons Laws of motion is much similar to the Guna Siddhanta. Conclusion : Laws of Motion can be understood through Guna Siddhanta.