COMPARATIVE PHASE 2 CLINICAL STUDY TO EVALUATE THE EFFICACY OF ASHVATTHA TWAK KASHAY AND GUDUCHI KASHAY IN VATARAKTA WITH SPECIAL REFERENCE TO GOUT

Abstract

Background-Vatarakta is said to be a lifestyle disorder which is caused due to consump-tion of junk food, high protein diet and sedentary lifestyle disturbing healthy environment of our society. Vatarakta is often compared with Gouty Arthritis in modern medicine due to its outstanding similarities in signs and symptoms of the disease. Gout is a disorder of purine metabolism and is an inflammatory response to the monosodium urate monohydrate crystals formed secondary to hyperuricaemia. The incidence of Gout varies in population from 0.2 to 3.5 per 1000 with overall prevalence 2 to 2.6 per 1000 in India. Worldwide its prevalence is increased. It affects 2.1 million people. So the need of hour is to develop a satisfactory and safe Ayurvedic regimen for the management of Vatarakta. Aims&Objectives: This study is done to control the progression of disease and to improve quality of life. Materiai&Methods: In this study 60 patients were selected randomly and divided 30 in each group. In trial group, patient was given Ashvattha Twak Kashay and in control group,Guduchi Kashay was given orally for 30 days. Observation was done on subjective parameters and objective parameter and analyzed statistically. Conclusion : On the basis of applied statistical test of significance Ashvattha Twak Kashay was found equally effective as Guduchi Kashay.